---
title: "Telehealth prescription routing — niche opportunity inside Healthcare"
url: https://signals.gitdealflow.com/niche-down/healthcare/telehealth-prescription-routing
description: "ePrescribe APIs that handle the controlled-substance + state-by-state mess."
source: VC Deal Flow Signal
---
# Telehealth prescription routing

> ePrescribe APIs that handle the controlled-substance + state-by-state mess.

**Sector**: [Healthcare](https://signals.gitdealflow.com/niche-down/healthcare)  
**Build cost**: One-quarter build  
**Deal velocity**: Steady — one deal per month

## Why now

Telehealth is permanent. Every new telehealth app needs eRx. Most rebuild it from scratch poorly.

## What the signal looks like

Repos with Surescripts adapters, DEA EPCS compliance flows, and state-specific routing logic.

## Public examples

*Public projects + categories only — we never name founders tracked inside the paid product.*

- DoseSpot-style eRx APIs
- Photon Health shape
- Open-source eRx integrations

## What this displaces

A solo founder spending six months on Surescripts integration.

## Our build-vs-invest call

Infra wedge for the telehealth long tail. Sell to 100-1000 telehealth apps. Pricing per script. The moat is compliance + reliability — both hard to fake.

## Frequently asked

### Who's the buyer?

Telehealth platforms and direct-to-consumer health brands.

### Margin?

Per-script fee, 30-60% gross margin.

### What kills this?

Surescripts shipping a public API. Unlikely for years.

## Canonical

https://signals.gitdealflow.com/niche-down/healthcare/telehealth-prescription-routing